Prozac (Fluoxetine) [prescription drug, generic available]:
Prozac (like paxil, zoloft, etc.) affects neurotransmitters, the chemicals that nerves within the brain use to communicate with each other. Neurotransmitters are manufactured and released by nerves and then travel and attach to nearby nerves and can be thought of as the communication system of the brain. Serotonin is one such neurotransmitter. The serotonin either travels across the space between nerves and attaches to receptors on the surface of nearby nerves or it attaches to receptors on the surface of the nerve that produced it, to be taken up by the nerve and released again (a process referred to as re-uptake). Prozac works by preventing the reuptake of one neurotransmitter, serotonin, by nerve cells after it has been released. The reduced uptake of serotonin caused by fluoxetine (Prozac) causes increased brain levels of serotonin, which changes mood. Prozac is prescribed for treating depression, bulimia, obsessive-compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder (PMDD).
Side Effects of Prozac: Many, many different side effects with the most common being (percentage of people with this side effect in brackets): nausea (up to 22%), insomnia (up to 19%), nervousness (up to 13%), anxiety (up to 12%), somnolence (up to 12%), diarrhea (up to 11%), anorexia (up to 10%).
Comparisons with Other Anti-Depressants: A recent study indicated that the three most commonly prescribed anti-depressants had about the same effectiveness. Drugs tested were paxil (paroxetine), prozac (fluoxetine) and zoloft (sertrraline). This study followed 573 primary care depressed patients for nine months, well beyond the acute phase of depression. The patients were randomized to one of the three drugs. While similar tests do not yet seem available for two newer antidepressants, wellbutrin and lexapro, it is likely that they are also equally effective. For specific side effects of these others... Paxil Side Effects Zoloft Side Effects Wellbutrin Side Effects Lexapro Side Effects. The above study was published in the Journal of the American Medical Association Dec 19, 2001. FURTHER NOTE: some evidence suggests that drugs like Prozac can cause unwanted sexual changes in desire, performance and satisfaction.
Popular Prozac Sites
- Prozac Answers
Offers comprehensive answers to questions regarding all aspects of using Prozac.
Website offers complete drug monograph from Internet Mental Health.
- Fluoxetine Info
A clearly laid out site offering info on how Fluoxetine works.
Info from the RxList regarding chemical composition, brand names and category.
Official manufacturers website for detailed info about this drug.
- Prozac Truth
The Prozac approval process described. Also side effects of other SSRIs and other types of medication.
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